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An enthusiast photographer, blogger and dreamer. Currently a 5th year medical student in Mansoura, Egypt. Hometown in Malaysia

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John Forbes Nash, Jr.

Friday, May 21, 2010





Background

John Forbes Nash, Jr. (born June 13, 1928) is an American economist and mathematician whose works in game theory, differential geometry, and partial differential equations have provided insight into the forces that govern chance and events inside complex systems in daily life. His theories are used in market economics, computing, evolutionary biology, artificial intelligence, accounting and military theory. Serving as a Senior Research Mathematician at Princeton University during the later part of his life, he shared the 1994 Nobel Memorial Prize in Economic Sciences with game theorists Reinhard Selten and John Harsanyi.

Nash is the subject of the Hollywood movie A Beautiful Mind. The film, based rather loosely on the biography of the same name, focuses on Nash's mathematical genius and struggle with paranoid schizophrenia.


Early life

Nash was born on June 13, 1928 in Bluefield, West Virginia. His father, after whom he is named, was an electrical engineer for the Appalachian Electric Power Company. His mother, Margaret, had been a school teacher prior to marriage. Nash's parents pursued opportunities to supplement their son's education with encyclopaedias and even allowed him to take advanced mathematics courses at a local college while still in high school. Nash accepted a scholarship to Carnegie Institute of Technology (now Carnegie Mellon University) and graduated with a Master's Degree in only three years.


Post-graduate life

Nash's advisor and former Carnegie Tech professor, R.J. Duffin, wrote a letter of recommendation consisting of a single sentence: "This man is a genius." Nash was accepted by Harvard University, but the chairman of the mathematics department of Princeton, Solomon Lefschetz, offered him the John S. Kennedy fellowship, which was enough to convince Nash that Harvard valued him less. Thus he went to Princeton where he worked on his equilibrium theory. He earned a doctorate in 1950 with a 28 page dissertation on non-cooperative games. The thesis, which was written under the supervision of Albert W. Tucker, contained the definition and properties of what would later be called the "Nash Equilibrium". These studies led to four articles:

"Equilibrium Points in N-person Games", Proceedings of the National Academy of Sciences 36 (1950), 48–49. MR0031701

"The Bargaining Problem", Econometrica 18 (1950), 155–162. MR0035977

"Two-person Cooperative Games", Econometrica 21 (1953), 128–140. MR0053471

"Non-cooperative Games", Annals of Mathematics 54 (1951), 286–295.

Nash did ground-breaking work in the area of real algebraic geometry:

"Real algebraic manifolds", Annals of Mathematics 56 (1952), 405–421. MR0050928

See Proc. Internat. Congr. Math. (AMS, 1952, pp 516–517).

His most famous work in mathematics is the Nash embedding theorem, which shows that any abstract Riemannian manifold can be isometrically realized as a sub-manifold of Euclidean space. He made contributions to the theory of non-linear parabolic partial differential equations, and to singularity theory.


Personal life

As per Nash's biography, from 1951 onwards, he had a liaison with a nurse, named Eleanor Stier. They bore a child named John David Stier. Though Nash had thought of marrying her, he later decided against it and abandoned them.

In 1955, Nash went to the Massachusetts Institute of Technology as a C. L. E. Moore Instructor in the mathematics faculty. There, he met Alicia López-Harrison de Lardé (born January 1, 1933), a woman from El Salvador, whom he married in February 1957. She admitted Nash to a mental hospital in 1959 for schizophrenia; their son, John Charles Martin Nash, was born soon afterward, but remained nameless for a year because his mother felt that her husband should have a say in the name.

Nash won the Nobel Memorial Prize in Economic Sciences in 1994.


Schizophrenia

Nash began to show signs of extreme paranoia and his wife later described his behaviour as erratic, as he began speaking of characters who were putting him in danger. Nash seemed to believe that there was an organization chasing him, in which all men wore red ties. Nash mailed letters to embassies in Washington, D.C., declaring that they were establishing a government.


He was admitted to the McLean Hospital, April–May 1959, where he was diagnosed with paranoid schizophrenia. It is the most common type of schizophrenia in most parts of the world. The clinical picture is dominated by relatively stable, often paranoid, fixed beliefs that are either false, over-imaginative or unrealistic, usually accompanied by experiences of seemingly real perception of something not actually present—particularly auditory and perceptional disturbances, a lack of motivation for life, and mild clinical depression. Upon his release, Nash resigned from MIT, withdrew his pension, and went to Europe, unsuccessfully seeking political asylum in France and East Germany. He tried to renounce his U.S. citizenship. After a problematic stay in Paris and Geneva, he was arrested by the French police and deported back to the United States at the request of the U.S. government.


In 1961, Nash was committed to the New Jersey State Hospital at Trenton. Over the next nine years, he spent periods in psychiatric hospitals, where, aside from receiving anti-psychotic medications, he was administered insulin shock therapy.


Although he took prescribed medication, Nash wrote later that he only took it under pressure. After 1970 he was never committed to the hospital again and refused any medication. According to Nash, the film A Beautiful Mind inaccurately showed him taking new atypical anti-psychotics during this period. He attributed the depiction to the screenwriter (whose mother, he notes, was a psychiatrist), who was worried about encouraging people with the disorder to stop taking their medication. Others, however, have questioned whether the fabrication obscured a key question as to whether recovery from problems like Nash's can actually be hindered by such drugs, and Nash has said they are overrated and that the adverse effects are not given enough consideration once someone is considered mentally ill. According to Nasar, Nash recovered gradually with the passage of time. Encouraged by his then former wife, De Lardé, Nash worked in a communitarian setting where his eccentricities were accepted. De Lardé said of Nash, "it's just a question of living a quiet life".


Nash dates the start of what he terms "mental disturbances" to the early months of 1959 when his wife was pregnant. He has described a process of change "from scientific rationality of thinking into the delusional thinking characteristic of persons who are psychiatrically diagnosed as 'schizophrenic' or 'paranoid schizophrenic' including seeing himself as a messenger or having a special function in some way, and with supporters and opponents and hidden schemers, and a feeling of being persecuted, and looking for signs representing divine revelation. Nash has suggested his delusional thinking was related to his unhappiness, and his striving to feel important and be recognized, and to his characteristic way of thinking such that "I wouldn't have had good scientific ideas if I had thought more normally." He has said, "If I felt completely pressureless I don't think I would have gone in this pattern". He does not see a categorical distinction between terms such as schizophrenia and bipolar disorder. Nash reports that he did not hear voices until around 1964, later engaging in a process of rejecting them. Nash reports that he was always taken to hospitals against his will, and only temporarily renounced his "dream-like delusional hypotheses" after being in a hospital long enough to decide to superficially conform, behave normally or experience "enforced rationality". Only gradually on his own did he "intellectually reject" some of the "delusionally influenced" and "politically-oriented" thinking as a waste of effort. However, by 1995, he felt that although he was "thinking rationally again in the style that is characteristic of scientists", he felt more limited.

article taken from Wikipedia


Ozone Layer

Thursday, May 6, 2010

Whatever Happened to the Hole in the Ozone Layer?

Three British scientists shocked the world when they revealed on May 16th, 1985 - 25 years ago - that aerosol chemicals, among other factors, had torn a hole in the ozone layer over the South Pole. The ozone layer, which protects life on Earth from damaging solar radiation, became an overnight sensation. And the hole in the ozone layer became the poster-child for mankind's impact on the planet.

Today, the ozone hole - actually a region of thinned ozone, not actually a pure hole - doesn't make headlines like it used to. The size of the hole has stabilized, thanks to decades of aerosol-banning legislation. But, scientists warn, some danger still remains.

First, the good news: Since the 1989 Montreal Protocol banned the use of ozone-depleting chemicals worldwide, the ozone hole has stopped growing. Additionally, the ozone layer is blocking more cancer-causing radiation than any time in a decade because its average thickness has increased, according to a 2006 United Nations report. Atmospheric levels of ozone-depleting chemicals have reached their lowest levels since peaking in the 1990s, and the hole has begun to shrink.

Now the bad news: The ozone layer has also thinned over the North Pole. This thinning is predicted to continue for the next 15 years due to weather-related phenomena that scientists still cannot fully explain, according to the same UN report . And, repairing the ozone hole over the South Pole will take longer than previously expected, and won't finish until between 2060 and 2075. Scientists now understand that the size of the ozone hole varies dramatically from year to year, which complicates attempts to accurately predict the hole's future size.

Interestingly, recent studies have shown that the size of the ozone hole affects the global temperature. Closing the ozone hole actually speeds up the melting of the polar ice caps, according to a 2009 study from Scientific Committee on Antarctic Research.

So even though environmentally friendly laws have successfully reversed the trend of ozone depletion, the lingering effects of aerosol use, and the link between the ozone hole and global warming, virtually ensure that this problem will persist until the end of the century.


article is from Yahoo!

Lack of sleep linked to early death

Wednesday, May 5, 2010

Lack of sleep linked to early death: study

LONDON (AFP) – People who get less than six hours sleep per night have an increased risk of dying prematurely, researchers said on Wednesday.

Those who slumbered for less than that amount of time were 12 percent more likely to die early, though researchers also found a link between sleeping more than nine hours and premature death.

"If you sleep little, you can develop diabetes, obesity, hypertension and high cholesterol," Francesco Cappuccio, who led research on the subject at Britain's University of Warwick, told AFP.

The study, conducted with the Federico II University in Naples, Italy, aggregated decade-long studies from around the world involving more than 1.3 million people and found "unequivocal evidence of the direct link" between lack of sleep and premature death.

"We think that the relation between little sleep and illness is due to a series of hormonal and metabolical mechanisms," Cappuccio said.

The findings of the study were published in the Sleep journal.

Cappuccio believes the duration of sleep is a public health issue and should be considered as a behavioural risk factor by doctors.

"Society pushes us to sleep less and less," Cappuccio said, adding that about 20 percent of the population in the United States and Britain sleeps less than five hours.

Sleeping less than six hours is "more common amongst full-time workers, suggesting that it may be due to societal pressures for longer working hours and more shift work"

The study also found a link between sleeping more than nine hours per night and premature death, but Cappuccio said oversleeping is more likely to be an effect of illness, rather than a cause.

"Doctors never ask how much one sleeps, but that could be an indicator that something is wrong," said Cappuccio, who heads the Sleep, Health and Society Programme at the University of Warwick.

Research showed no adverse effects for those sleeping between six and eight hours per day.


p.s: nasihat pada diri sendiri- jagalah tidur anda!!

Expectant Mom's Exercise Keeps Newborn's Birth Weight Down

Tuesday, April 6, 2010

MONDAY, April 5 (HealthDay News) -- Regular moderate-intensity exercise during pregnancy reduces an infant's birth weight, which may lower the child's risk of obesity later in life, researchers say.

In a new study, 84 first-time pregnant women were randomly assigned to exercise or control groups, with those in the exercise group participating in a weekly maximum of five 40-minute sessions on a stationary cycle. They did this program until at least 36 weeks into their pregnancy.

Babies born to mothers in the exercise group were an average of 143 grams lighter than infants born to mothers in the control group, and also had a lower body-mass index (a measurement that takes into account height and weight), the researchers found.

The exercise training had no effect on the mothers' body weight or body-mass index during late pregnancy, and had no effect on insulin resistance from the start of the study to late gestation, according to the report published online in the Journal of Clinical Endocrinology & Metabolism.

"Our findings show that regular aerobic exercise alters the maternal environment in some way that has an impact on nutrient stimulation of fetal growth, resulting in a reduction in offspring birth weight," study co-author Dr. Paul Hofman, of the University of Auckland in New Zealand, said in an Endocrine Society news release. "Given that large birth size is associated with an increased risk of obesity, a modest reduction in birth weight may have long-term health benefits for offspring by lowering this risk in later life."

Hofman added that the "physiological response to pregnancy appears to supersede the chronic improvements in insulin sensitivity previously described in response to exercise training in non-pregnant individuals. This may be an important finding for athletes who want to continue regular training during their pregnancy as it suggests that training will not have a major adverse impact on insulin resistance."


SOURCE: The Endocrine Society, news release, April 5, 2010

HealthDay

data obtain from: http://www.nlm.nih.gov/medlineplus/news/fullstory_97212.html

Barotrauma

Monday, April 5, 2010

What is Barotrauma?

Barotrauma refers to injury sustained from failure to equalize the pressure of an air-containing space with that of the surrounding environment. The most common examples of barotrauma occur in air travel and scuba diving. Although the degree of pressure changes are much more dramatic during scuba diving, barotraumatic injury is possible during air travel.

Barotrauma can affect several different areas of the body, including the ear, face and lungs. Here we will focus on barotrauma as it relates to the ear.


What are the Symptoms of Barotrauma?

Symptoms of barotrauma include “clogging” of the ear, ear pain, hearing loss, dizziness, ringing of the ear (tinnitus), and hemorrhage from the ear.

Dizziness (or vertigo) may also occur during diving from a phenomenon known as alternobaric vertigo. It is caused by a difference in pressure between the two middle ear spaces, which stimulates the vestibular (balance) end organs asymmetrically, thus resulting in vertigo. The alternobaric response can also be elicited by forcefully equalizing the middle ear pressure with the Politzer maneuver, which can cause an unequal inflation of the middle ear space.

What Causes Barotrauma?

Barotrauma is caused by a difference in pressure between the external environment and the internal parts of the ear. Since fluids do not compress under pressures experienced during diving or flying, the fluid-containing spaces of the ear do not alter their volume under these pressure changes. However, the air-containing spaces of the ear do compress, resulting in damage to the ear if the alterations in ambient pressure cannot be equalized. Rarely, barotrauma may be the result of hyperbaric oxygen therapy. Slow compression hyperbaric oxygen therapy is associated with a lower risk of otoc barotraumas than traditional hyperbaric oxygen therapy.

Barotrauma can affect the outer, middle, or inner ear.


How is Barotrauma Diagnosed?

Diagnosis is initially based on careful history. If the history indicates ear pain or dizziness that occurs after diving or an airplane flight, barotrauma should be suspected. The diagnosis may be confirmed through ear examination, as well as hearing and vestibular testing.


How is Barotrauma Treated?

For outer ear barotrauma, the treatment consists of clearing the ear canal of the obstruction, and restricting diving or flying until the blockage is corrected and the ear canal and drum return to normal.

For middle ear barotrauma, treatment consists of keeping the ear dry and free of contamination that could cause infection. Topical nasal steroids and decongestants may be started in an attempt to decongest the eustachian tube opening. The presence of pus may prompt the use of appropriate antibiotics. Most tympanic membrane perforations due to barotrauma will heal spontaneously. If the eustachian tube demonstrates chronic problems with middle ear equalization, the likelihood of recovery is drastically reduced.

Prevention of air barotraumas to the middle ear has been attempted with dasal decongestants or vasoconstrictors with mixed results. “Pressure equalizing” ear plugs claiming to prevent in-flight barotrauma are available in many airports for purchase. A trial evaluating the effect of these earplugs to placebo found them to have no effect on barotrauma.

For inner ear barotrauma, treatment consists of hospitalization and bed rest with the head elevated 30 to 40 degrees. Controversy exists whether this type of injury needs immediate surgery. Once healed, a diver should not return to diving until hearing and balance function tests are normal.


this information is taken directly from American Hearing Research Foundation. More information can be obtain at its website.

Another Reason To Quit Smoking

Thursday, April 1, 2010


CIGARETTES may contain traces of pigs' blood, an Australian academic says with a warning that religious groups could find its undisclosed presence "very offensive".

University of Sydney Professor in Public Health Simon Chapman points to recent Dutch research which identified 185 different industrial uses of a pig - including the use of its haemoglobin in cigarette filters.

Prof Chapman said the research offered an insight into the otherwise secretive world of cigarette manufacture, and it was likely to raise concerns for devout Muslims and Jews.

Religious texts at the core of both of these faiths specifically ban the consumption of pork.

"I think that there would be some particularly devout groups who would find the idea that there were pig products in cigarettes to be very offensive," Prof Chapman said today.

"The Jewish community certainly takes these matters extremely seriously and the Islamic community certainly do as well, as would many vegetarians.

"It just puts into hard relief the problem that the tobacco industry is not required to declare the ingredients of cigarettes ... they say 'that's our business' and a trade secret."

The Dutch research found pig haemoglobin - a blood protein - was being used to make cigarette filters more effective at trapping harmful chemicals before they could enter a smoker's lungs.

Prof Chapman said while tobacco companies had moved voluntarily list the contents of their products on their websites, they also noted undisclosed "processing aids ... that are not significantly present in, and do not functionally affect, the finished product".

This catch-all term hid from public view an array of chemicals and other substances used in the making of tobacco products, he said.

At least one cigarette brand sold in Greece was confirmed as using pig haemoglobin in its processes, Prof Chapman said, and the status of smokes sold was unknown.

"If you're a smoker and you're of Islamic or Jewish faith then you'd probably would want to know and there is no way of finding out," Prof Chapman said.

The Sydney office of British American Tobacco Australia was contacted by AAP.

A spokeswoman said a comment would be provided although it was not immediately available.

Paul Meier Dialect Services

Saturday, February 27, 2010

http://www.paulmeier.com/index.html

Whether you're an actor wanting instruction and coaching in dialects, voice-over, or Shakespeare; an ESL student;a regional dialect speaker needing "accent reduction;" or someone who wants to learn an accent just for fun, you've come to the right place! Paul Meier has been teaching British and American dialects (Yorkshire dialect, Scottish dialect, Cockney dialect, New York dialect, etc.), and foreign language accents (French accent, German accent, Russian accent etc.) for over 30 years in the U.S.A. and his native England, coaching some of the biggest names in movies — Tobey Maguire of Spiderman fame, for example — and hundreds of plays, films, and musicals. With his long experience as a voice-over artist (the voice of Wal-mart's Smiley), and as an actor in audio books (Ayn Rand's Anthem), he's uniquely qualified to help others in these fields. Welcome to Paul Meier Dialect Services.



 
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